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These two sides have a chance to put pressure on Atletico at the top of the standings before Diego Simeone’s men face a tricky trip to Real Betis a day later.
Having already departed the Champions League, Barcelona have extra time to prepare for this clash, but their hosts are used to managing a European schedule and their win over Liverpool midweek will have raised spirits in the camp.
Barca can point to some excellent league form as they arrive with 16 wins from 19 unbeaten games, including 13 from 14 in 2021 so far. However, across all competitions, they haven’t always stood up in their biggest tests this season.
Facing fellow top-four outfits Real Madrid, Atletico and Sevilla domestically, as well as PSG and Juventus in Europe, the Catalans are a disappointing W2-D2-L5 over the campaign as they’re yet to truly convince under Ronald Koeman.
Zinedine Zidane faced some questions earlier in the season, but his team have now won 10 of 12 unbeaten games since the start of February as they’ve built some momentum of their own.
However, while they haven’t conceded more than once in any of these games, it’s now seven appearances without a clean sheet as even that was achieved hosting lowly Eibar.
Real Madrid Draw No Bet
They should struggle to shut their opponents out here with something of a defensive crisis at the moment.
Centre-backs Sergio Ramos and Raphael Varane are absent, as is right-back Dani Carvajal, so a similar team to the one that faced Liverpool should be expected here.
Still, Nacho and Eder Militao marshalled the defence well in that encounter, as Barcelona shouldn’t expect to have a free pass to goal.
The Catalans have their own concern at centre-back with veteran Gerard Pique in a race against time to recover from a knee injury, though should he make the cut then Frenkie De Jong could find himself back in his favourite position in midfield.
There’s also a question over Sergi Roberto’s availability, while attacking duo Ansu Fati and Philippe Coutinho are ruled out.
Barcelona have won seven of eight unbeaten games in all competitions, though were unimpressive last time out as they had to wait 90 minutes before Ousmane Dembele eventually found the breakthrough.
They look too short at the prices for a team that has struggled in the big games and Real have certainly had the better of recent head to heads, winning two of three unbeaten clashes since the start of last season, including a 3-1 win at the Nou Camp earlier this season.